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Volume 1

Review Articles

1.

YOGA : FUTURE CURE FOR THE MENTAL ILLNESS AS WELL AS OTHER SEVERE DISEASE

Now days a mental illness is going to overtake all health problems in all over the world. The cause is busy schedule of daily life and so many. Among all the available treatments, yoga proved as best treatment for the mental illness according to studies. As yoga is used since the ancient time to cure not only the mental illness but also used for the several severe diseases. In this review we will study about the yoga as a best future treatment for the mental as well as the severe disease spread around.

Pratap Shankar*, Anjula Sachan, Dheeraj, Amod Kumar Sachan, Rajendra Nath, Rakesh Kumar Dixit

Department of Pharmacology & Therapeutics, King George's Medical University, Lucknow, India

49-50
2.

HPV – ANOTHER GREAT CAUSE OF ORAL CANCER

HPV oral and oropharyngeal cancers are harder to discover than tobacco related cancers. HPV manifests itself primarily in the posterior regions such as the base of the tongue, the back of the throat, the tonsils, the tonsillar crypts, and tonsillar pillars. HPV is the most common sexually transmitted virus and infection. HPV is driving the growth in numbers of oral cancers every year by about 10%. It can be caused because of the greater number of sexual partners, when engaging in oral sex, this also holds true for oral infections. HPV is passed on through genital contact, most often during vaginal, anal and oral sex. We are more likely to get HPV if we have weakened immune systems also. Many people don't have symptoms and are unaware that they have HPV. The virus may be inactive for weeks, months and for some people possibly even years after infection. The CDC now recommends an HPV test for women along with the PAP test as a matter of routine. Oral HPV testing in both men and women is problematic. There are anal brush cytology tests for those that engage in anal sexual practices.

Shainda Laeeq*, Dr. Suman Rao Vihari, Istafa Husain Khan

*Lecturer, Department of Pharmacology, Maharana Pratap Dental College, Mandhana, Kanpur.

51-55

Research Articles

3.

DEVELOPMENT AND EVALUATION OF NUTRITIONAL QUALITY OF ANTIOXIDANT RICH PRODUCTS USING DRUMSTICK (Moringa oleifera) AND AMARANTH (Amaranthus tricolor) LEAVES POWDER

Drumstick (Moringa oleifera) and amaranth (Amaranthus tricolor) leaves are rich source of protein, â- carotene, ascorbic acid and minerals. The aim of the present study was to standardize and organoleptically evaluate drumstick leaves powder (DLP) and amaranth leaves powder (ALP) incorporated recipes with their nutritional evaluation. Products namely dal, pulao and khichri at 25% and 30% level were prepared by incorporating these powders and control. Proximate analysis and vitamin content of products were estimated. Results showed that 25% level of supplementation in dal, pulao and khichri were highly acceptable, with an overall acceptability score of 7.65 (25% DLP) and 7.37 (25% ALP) for dal and 8.20 (25% DLP) and 7.52 (25% ALP) for pulao whereas 8.05 (25% DLP) and 7.87 (25% ALP) for khichri. Dal supplemented at 25% level of DLP had 21.40% protein, 6.92% crude fat, 5.34% crude fibre, 3.65% total ash and 398Kcal energy whereas dal with 25% ALP had 21.20% crude protein, 6.32% crude fat, 4.02% crude fibre, 4.63% total ash and 397 Kcal energy. Pulao supplemented at 25% level of DLP had 10.84% protein, 6.52% crude fat, 4.39% crude fibre, 3.02% total ash and 402Kcal energy whereas pulao with 25% ALP had 9.23% crude protein, 6.01% crude fat, 3.14% crude fibre, 4.10% total ash and 401 Kcal energy. Khichri supplemented at 25% level of DLP had 11.53% protein, 5.62% crude fat, 4.46% crude fibre, 3.59% total ash and 395Kcal energy whereas khichri with 25% ALP had 11.42% crude protein, 5.05% crude fat, 3.21% crude fibre, 4.57% total ash and 394 Kcal energy. These results reveal that the leaves contain an appreciable amount of nutrients and can be included in diets to supplement our daily nutrient needs.

Shalini Kushwaha*, Paramjit Chawla

*Assistant Professor, Department of Food Science and Technology Babasaheb Bhimrao Ambedkar University, Lucknow-226002

01-07
4.

COMPARISON OF MULTI-STATION WEIGHT BEARING PROPRIOCEPTIVE EXERCISE IN SUBJECTS WITH KNEE OSTEOARTHRITIS

Knee osteoarthritis (KOA) is one of the most common diseases which advance with age. It appears no single treatment is sufficient to effectively manage KOA. Diminished strength and proprioceptive acuity are associated risk factors in preventive as well as curative measures. Hence, this investigation was designed to determine the effects of weight bearing proprioceptive exercise in enhancing strength and proprioception in patients with KOA. Randomised trial with concealed allocation and intention-to-treat analysis. A population sample referred in physiotherapy department with diagnosed KOA was included. Variables such as age, sex, height, body weight and body mass index (BMI) was evaluated. Gender wise group distribution was done. Weight bearing proprioceptive training and strengthening exercises was given on alternate day. Treatment session was 6 days a week for 4 week. The data for knee pain, functional disability and proprioceptive acuity were collected and analyzed on the first day and after 4 weeks. There was significant reduction in pain, improved function and proprioceptive acuity in both groups (p< 0.05) but no significant difference between the groups. This study concluded that combined weight bearing Proprioceptive and strengthening exercises are effective in reducing pain and improving function and proprioception in subjects with knee osteoarthritis.

Suraj Kumar*, Ashish Kumar, V.P. Sharma

*Associate Professor and HOD, Department of PT at RIMS & R

08-15
5.

A STUDY ON EVALUATION OF PRIMARY IMMUNIZATION COVERAGE IN THE SLUMS OF KANPUR NAGAR

In 2008, WHO estimated that 1.5 million of deaths among children under 5 years were due to diseases that could have been prevented by routine vaccination. This represents 17% of global total mortality in children under 5 years of age. Present study was conducted to cover the immunization of children aged 12-23 months in the slums of Kanpur Nagar.

Ruchi Chaturvedi *, R.P. Sharma, D.S. Martolia, Seema Nigam, Punit Varma, Tanu Midha, Yashwant Kumar Rao

*Ex -Resident, Department of Community Medicine, GSVM Medical College, Kanpur(Uttar Pradesh)

16-19
6.

MATERNAL SOCIO-DEMOGRAPHIC DETERMINANTS OF STILLBIRTH : A HOSPITAL BASED STUDY

Occurrence of stillbirth is a tragic event faced by the obstetrician. It has many implications for the couple, family and the health care provider. It reflects a failure or lapse in implementation of maternal and child health care programme. For many reasons, stillbirth has been under-studied, under-reported, and rarely considered in attempts to improve pregnancy outcomes in low-income countries.25 Hence an effort was made to know the influence of mother's socio-biological factors on stillbirth. Object of this study was to determine maternal socio-biological factors influencing still-birth. Hospital based cross- sectional study undertaken in Post Natal Care (PNC) wards of Nehru hospital, Gorakhpur. The study period extended from July 2011 to August 2012. The study subject included recently delivered mothers and data was collected on semi-structured interview schedule to know various socio-biological variables such as mother's age, parity, inter-pregnancy interval etc, influencing the stillbirth. Chi-Square test was applied to observe the significance of association.

Samarjeet Kaur* , A.K. Upadhyay , D.K. Srivastava, Reena Srivastava, O.N. Pandey

Lecturer, Department of Community Medicine, GSVM Medical College, Kanpur, Uttar Pradesh

20-25
7.

FORTIFICATION OF MICONUTRIENT WITH STEVIA LEAF IN WHEAT BASED FOOD PRODUCT

In this study, the wheat refined flour bun prepared by standardized method and fortified by two way natural source (stevia leaf powder) and synthetic source (edible folic acid powder). The result were analyzed for physical or sensor characteristic by 9 point hedonic scale and nutritional characteristic by standardized method. In the highest folic acid content found in synthetic bun. Moisture content in synthetic bun was also found higher than control and stevia bun sample.

Swati Sachan*, Praveen Katiyar, Vivek Singh Sachan, Warshi Singh

Guest Assistant Professor, University Institute of Health Sciences, CSJM Univeristy, Kanpur.

26-28
8.

ANALYSIS OF SPECTRUM OF CHRONIC KIDNEY DISEASE IN IPD AND OPD PATIENTS OF SELECTED HOSPITALS OF LUCKNOW CITY

The health care burden due to chronic kidney disease has increased worldwide in past decade. Elucidating the spectrum of chronic kidney may help in identifying strategies for prevention of chronic kidney disease. So the present study was conducted in 2 tertiary care centers of Lucknow to analyze the spectrum of chronic kidney disease in IPD and OPD renal pateints. 100 chronic kidney disease patients (50 from indoor patient department and 50 from outdoor patient department) of more than 15 years of age, belonging to different socioeconomic status were selected and surveyed. A questionnaire-cum-interview schedule method was used which included demographic profile of patients, risk factors, common symptoms, complications, severity of disease etc. The findings concluded diabetes as a most prevalent risk factor among patients of both groups, followed by hypertension and other glomerular diseases. Vomiting, edema, nausea and abdominal pain were common in both groups. Anemia was found as the most prevalent complication, followed by hyperphosphatemia and hyponatremia. Other diseases like diabetes mellitus, high blood pressure, infections, CVD and obesity cause greater levels of morbidity and mortality among the population as a whole and kidney disease is important in large part because of its relationship with more common diseases. Early treatment can reduce the risk of developing more serious disease or can at least slow the rate at which the disease progresses.

Tanu Jain *, Seema Jaiswal, Praveen Katiyar

Research Scholar, Punjab Agriculture University, Punjab

29-33
9.

STATUS OF HEPATITIS B VACCINATION AMONG PERSONS INVOLVED IN HEALTH CARE SYSTEM OF KANPUR DISTRICT HOSPITAL

Person involved in health care system have a high risk of occupational exposure to many blood-borne diseases including Hepatitis B, and other viral infections. Hepatitis B is not only the most transmissible infection, but also the one of the preventable by vaccination. The present qualitative study was conducted to get a better understanding of participant's awareness regarding the challenges of working at health care system with particular reference with hepatitis B employed at the Ursala Horsmann Memorial District Hospital, & Cardiology Institute, Kanpur. A total of 56 screened person involved in the service of hospital were studied after getting their consent, all were explained about the objective of the study and were asked to fill a standard questionnaire regarding the same.

Maneesh Kumar Singh*, Aditya Gupta, Ajay Kumar Gupta

Associate Professor, University Institute of Pharmacy C.S.J.M. University, Kanpur (U.P.) India

34-39
10.

ADA AND CRP: NOVEL DIAGNOSTIC MARKERS FOUND IN TB PATIENTS

In present study some tuberculous cases were investigated for biochemical parameters such as ADA and CRP, it is found that, the sensitivity and specificity for serum concentration is 98% and 100% of serum ADA concentration and CRP, respectively. After the study, the result confirms the high sensitivity and specificity of ADA test for really diagnosis of TB in cases of serous effusion. The selective enzyme increase in tuberculous peritonitis strongly supports the concept that the study of ADA activity is of great value for identifying the tuberculosis etiology of ascites. ADA has been proposed to be a useful surrogate marker for TB in pleural, pericardial and peritoneal fluids. High levels of serum CRP indicate that it is also a good indicator of the severity and progress of the tuberculosis. Cytological examination of suspected malignant pleural effusion can result in false-negative rates of up to 40%. Diagnostic difficulties have led to the search of novel markers. Pleural fluid ADA and CRP levels were established to be significantly higher in tuberculous and parapneumonic effusions (PPES) when compared with other pleural effusions. Pleural fluid ADA and CRP levels can be a useful combination in the differential diagnosis of pleural effusions of malignant, tuberculous, and parapneumonic nature.

Dr. Suman Rao Vihari*, Shainda Laeeq, Istafa Husain Khan

*Lecturer, Dept. of Biochemistry, Maharana Pratap Dental College, Mandhana.

40-42
11.

NUTRITIONAL STATUS & AWARENESS OF FEMALES PURSUING HIGHER EDUCATION

India is the leading developing country of the world and witnessed many changes in social, cultural, economical and demographical domains. These forces cause the various domino effects in the society. Above all effects, change in women contribution has significance impact on the society. But, when it comes to the nutritional status of women in India, it is always subjected to negligence. In 21st century, when realm of women get liberalised and number of working women is increasing day by day, this overloading of responsibilities is causing the problem of mal- nutrition among literate women as well. Present study tries to explore the various nutritional problem of women pursuing higher studies and as well as analyse their nutritional status. Qualitative and quantitative mixed research approach is used to get the better holistic understanding of the issues. Findings highlighted that in spite of having awareness about many nutritional aspects and standard female pursuing higher studies were not able maintain their nutritional level up to the mark. This study has number of implications for working women as well as female pursuing higher studies.

Shalini Shukla*

NET, M.Sc. (Food & Nutrition) University of Lucknow, Lucknow

43-48
12.

FORTIFICATION OF MICONUTRIENT WITH STEVIA LEAF IN WHEAT BASED FOOD PRODUCT

In this study, the wheat refined flour bun prepared by standardized method and fortified by two way natural source (stevia leaf powder) and synthetic source (edible folic acid powder). The result were analyzed for physical or sensor characteristic by 9 point hedonic scale and nutritional characteristic by standardized method. In the highest folic acid content found in synthetic bun. Moisture content in synthetic bun was also found higher than control and stevia bun sample.

Swati Sachan*, Praveen Katiyar, Vivek Singh Sachan, Warshi Singh

Guest Assistant Professor, University Institute of Health Sciences, CSJM Univeristy, Kanpur.

26-28
13.

Yogic Intervention and its effect on Hypertensive Patients

Hypertension, a “psychological classical silent killer” is the hallmark of various cardiovascular disorders. Hypertension wil become a greater global burden in the next 15 - 20 years. Hypertension is an important and growing public health challenge worldwide. If one believes that 'old is gold', then yoga is quite effective and widely believed to reduce blood pressure. The present society modified lifestyle and food pattern create various types of disorders such as Obesity, Diabetes and Hypertension. Hypertension is a one of the psycho-somatic disease. is highly beneficial in the case of hypertension patients. The aim of the present research is to study the Yogic intervention and its effect on hypertensive patients.Total numbers of 20 Hypertension patients in the age group of (30 to 60 yrs.) were randomly selected from Polyclinic, Dev Sanskriti Vishwavidyalaya, Gayatrikunj, Haridwar through the method of accidental sampling. In this study “Experimental Control group design” was used and t-test has been used for statistical analysis. The result showed a significant changes (p<0.01). The finding reveals that significantly reduced the level of systolic and diastolic blood pressure of the hypertensive. Therefore this Research Paper was undertaken to find a safe and effective treatment for Hypertension that is free from any adverse effects and would maintain Blood Pressure. Yogic interventionsignificantly reduced the level of systolic and diastolic blood pressure of the hypertensive. Therefore this Research Paper was undertaken to find a safe and effective treatment for Hypertension that is free from any adverse effects and would maintain Blood Pressure.

Saraswati Devi*, Sudershan Kumar

*1PhD Scholar m Yoga, Dev Sanskriti Vishwavidhyalaya, Haridwar (UK)

56-60
14.

VITAMIN-A FORTIFICATION OF VANILLA ICE CREAM USING BEETROOT GREEN PULP

Present study was carried out with the objective to fortify vanilla ice cream with vitamin A using beet root green pulp at different levels of fortification & to assess enhanced nutritional quality of the developed product. A control and four experimental treatments were prepared with varying proportions of beetroot green pulp- 3%, 6%, 9%, and 12%. Organoleptic evaluation of the ice cream was carried out using 9-Point Hedonic scale. The data obtained was analyzed statistically using analysis of variance and critical different techniques. Estimation of vitamin A content of sample showed high improvement in nutritional value of vanilla ice cream with maximum value of 181.72 ìg. There was linear increase in calcium content of the product from 47mg- 59mg .

Shukla Sudha, Daniel Madhvi

* M.Sc. Student, Dept. of Nutrition, Isabella Thoburn College, Lucknow E mail id: madhvidaniel@gmail.com

61-64
15.

NUTRITIVE VALUE OF EVALUTION OF ALOE VERA BASED PRODUCTS

Aloe vera is the oldest medicinal plant ever known and the most applied medicinal plant worldwide. The first written records about the use of Aloe vera were found on over 6,000 years old clay tablets found in Mesopotamia.In recent years, considerable progress has been made in pharmacological research on Aloe vera and there has appeared in the market some aloe food, medicine, health care products and cosmetics, which seems to be very popular. Hence, the study was taken up to formulate food products like jams, laddus by adding Aloe vera. The samples prepared were analyzed for nutritional constituents using standard procedures (AOAC,1995). Aloe vera Laddus contained 34.21%, 39.52% and 45.91% moisture on D1, D2 and D3 respectively. The mean scores of protein content in samples of laddus were 6.02%, 5.06% and 4.11% on D1, D2 and D3 respectively. The mean score of Aloe veraladdus for fat were 17.82%, 16.40% and 15.28% on D1, D2 and D3 respectively. The mean score of carbohydrate content in Aloe vera laddus were 23.23%, 22.15% and 20.12% on D1, D2 and D3 respectively. The mean score of crude fibre content in Aloe vera laddus were 7.49%, 6.42% and 5.32% on D1, D2 and D3 respectively. Aloe vera jam contained 45.93%, 45.95% and 45.98% moisture on D1, D2 and D3 respectively. The mean scores of protein content in samples of jam were 5.03%, 5.06% and 5.09% on D1, D2 and D3 respectively. The mean score of fat content in Aloe vera jam was 3.2% on D1, D2 and D3. The mean score of carbohydrate content in Aloe vera jam was 25.89%, 27.83% and 27.90% on D1, D2 and D3 respectively. The mean score of crude fibre content in Aloe vera jam was 12.7%, 12.60% and 12.55% on D1, D2 and D3 respectively. Inclusion of such products in the diet of an individual can help in providing nourishment as well as the therapeutic benefits of Aloe, especially for its laxative and hypoglycaemic effect.

Dr.Vinita Singh*, Shubhra Mishra

Assistant Professor , Department of food science & Nutrition CSA University of Agriculture & Technology, Kanpur

65-68
16.

DOSE DEPENDENT IMPACT OF GERMINATED FENUGREEK SEED FLOUR SUPPLEMENTATION ON TYPE 2 DIABETICS

The present study was conducted to examine the dose dependent effect of germinated fenugreek seed flour on type 2 diabetics. This case control clinical trial was conducted on 30 type 2 diabetic subjects who were equally divided into 3 groups: experimental group 1 (EG-1), experimental group 2 (EG-2) and control group (CG). The EG-1 subjects were supplemented with20 g germinated fenugreek seed flour in chapatti twice a day and EG-2 patients with 20 g germinated fenugreek seed flour with water four times a day for 60 days.The metabolic parameters studied were fasting glucose, post prandial glucose, serum cholesterol, serum LDL, serum HDL, serum triglycerides, and serum VLDL. Significant reduction was recorded in serum glucose (23%), serum cholesterol (6%), serum LDL (20%) and a slight decrease in serum triglycerides and VLDL. Serum HDL increased significantly by 23 per cent. During the cross over randomized clinical trial, all metabolic parameters except for HDL increased upon stopping the supplementation. Thus, it is concluded that fenugreek seed flour as a low GI food product leads to modest improvement in long-term glycemic and lipidemic control in type 2 diabetics.

Hemlata Pandey* and Pratima Awasthi

*School for Home Sciences, Baba Saheb Bhimrao Ambedkar Central University, Lucknow

69-75